Background Illumina Infinium whole genome genotyping (WGG) arrays are increasingly being applied in malignancy genomics to study gene copy number alterations and allele-specific aberrations such as loss-of-heterozygosity (LOH). propose a quantile normalization strategy for correction of this dye bias. We tested the normalization strategy using 535 individual hybridizations from 10 data units from the analysis… Continue reading Background Illumina Infinium whole genome genotyping (WGG) arrays are increasingly being