Supplementary MaterialsSupplemental Data File _. group. PAB induced RV hypertrophy and fibrosis which were associated with improved manifestation of phospho-AKT. Interestingly, nitrite treatment attenuated PAB-induced RV hypertrophy and reduced the manifestation of phospho-Akt in RV cells from PAB mice. In neonatal rat cardiac fibroblast, nitrite also attenuated hypoxia-induced increase in manifestation of phospho-Akt. Conclusion Our… Continue reading Supplementary MaterialsSupplemental Data File _. group. PAB induced RV hypertrophy and