During development, spontaneous retinal activity is required for the refinement of connections throughout the developing visual system. retinal ganglion cells, AKAR, spontaneous activity, activity-dependent development, oscillations INTRODUCTION Neuronal activity is usually linked to long-term changes in cells, such as activity-dependent expression of genes, by activation of second messenger 1197958-12-5 manufacture 1197958-12-5 manufacture pathways (West et… Continue reading During development, spontaneous retinal activity is required for the refinement of