Supplementary Materialscancers-11-00210-s001. protein to enhance desensitization of breast malignancy cells to tamoxifen, while much like TARBP2, its induction in malignancy cells was SP600125 supplier also observed in metastatic tumor cells. Our results indicate the TARBP2-SOX2 pathway is definitely upregulated by tamoxifen-mediated Merlin downregulation, which consequently induces tamoxifen resistance in ER+ breast malignancy. value was less… Continue reading Supplementary Materialscancers-11-00210-s001. protein to enhance desensitization of breast malignancy cells to