Background Type 2 Diabetes Mellitus (T2DM) and menopause are connected with supplement D position. but higher among postmenopausal females. Adequate supplement D amounts in both groupings were associated with improved glucose control while hypovitaminosis D in the postmenopausal ladies was related to poorer glucose control. Vitamin D screening should be integrated into management plan for T2DM to serve as an early tool for prevention of vitamin D deficiency. 1. Introduction Type 2 Diabetes Mellitus (T2DM) is definitely a metabolic disease and major lifestyle disorder caused by either the complete or relative insulin deficiency. T2DM is characterized by impaired glucose tolerance, chronic hyperglycemia, and modified insulin secretion [1]. It affects more than 6% of obese urban Ghanaian adults, predominately women [2C4]. Accumulating evidence from various studies has linked vitamin D status to insulin secretion and insulin resistance [5C7]; however, the relationship between vitamin D deficiency and glycemic control remains conflicting. Vitamin D is definitely a steroid hormone known for its essential part in keeping calcium homeostasis, advertising and keeping bone health, and improving immune function [8, 9]. Vitamin D deficiency is considered a public health problem around the world. In 2008, it was estimated that 1 billion individuals present with vitamin D insufficiency or deficiency [10]. Vitamin Nutlin 3a distributor D is acquired through exposure to ultraviolet B (UVB) sunlight and also nutritional sources. Despite the high UVB sunlight publicity in tropical countries, studies suggest vitamin D deficiency is definitely prevalent and is definitely further influenced by age and gender [11, 12]. Menopause, the cessation of menstrual cycle caused by reduced secretions of estrogen and progesterone, is definitely defined as 1 year without menses, occurring between the ages of 45C55 [13]. Oestrogen increases the activity of 1-= is the critical value of the normal distribution (1.96 at 95% CI); is the estimated prevalence of T2DM in Ghana (6%); = 100 ? is the absolute precision or sampling error tolerated = 5%. From the above equation, a total of 192 Ghanaian ladies, 98 premenopausal and 94 postmenopausal clinically diagnosed with T2DM, living in Kumasi were recruited for the study. All respondents attended the Diabetic Clinic of the Komfo Anokye Teaching Hospital and had experienced diabetes for more than 6 months. 2.5. Questionnaire Administration Structured questionnaires were administered to obtain sociodemographic and medical history of study participants. The questionnaires were designed by reviewing earlier studies of similar objective and were tailored to fit our study objectives (face validity). The questionnaire was pilot tested; the data was entered into excel sheet and cleaned before it was administered to the study participants. 2.6. Inclusion and Exclusion Criteria Clinically diagnosed T2DM patients, 25 years and above, of Nutlin 3a distributor more than six weeks’ duration were included in the study. Respondents with osteoporosis, cancer, renal failure (renal osteodystrophy), and liver disease and those on medication that could impact glucose or lipid metabolism, Nutlin 3a distributor vitamin D metabolism or its absorption (phenytoin, rifampin, isoniazid, and ketoconazole), and calcium supplementation were excluded from the analysis. 2.7. BLOOD CIRCULATION PRESSURE Measurement Blood circulation pressure was measured with an automated blood circulation pressure apparatus (Omron MX3-Omron Matsusaka Co., Ltd. Japan) from the proper arm following the subjects have been sitting for approximately five a few minutes. The common of both readings taken 5 minutes aside was documented as the blood circulation pressure measurement. Hypertension was thought as a systolic blood circulation pressure 140?mm?Hg or diastolic blood circulation pressure 90?mm?Hg or background of previously known disease [20]. 2.8. Anthropometric Evaluation The GDNF fat of the chosen topics was measured in light clothes without shoes, within an upright placement to utilizing a calibrated analogue level (Seca, Hamburg, Deutschland) (the nearest 0.1?kg). Elevation was measured without shoes and boots utilizing a stadiometer (Seca, Hamburg, Deutschland) (to the nearest 0.1?cm). Waistline circumference (WC) and hip circumference (HC) had been measured (to the nearest 0.1?cm) with a measuring tape. All anthropometric measurements were completed on all respondents by same educated employees. Body mass index (BMI).