Great affinity binding of dihydrotestosterone (DHT) towards the androgen receptor (AR) initiates androgen-dependent gene activation necessary for normal male sex advancement gene may be the target for inhibition simply by abiraterone acetate. end up being synthesized within a so-called backdoor pathway (green) from progesterone and androsterone precursors 3rd party of DHEA, androstenedione or testosterone intermediates.… Continue reading Great affinity binding of dihydrotestosterone (DHT) towards the androgen receptor (AR)