After approval of warfarin in 1954, vitamin K antagonists (VKAs) continued to be the only real oral anticoagulant choice for over half of a century, despite challenges to safely and successfully manage them in daily practice. affected individual populations, with the proper dosing and suitable follow-up, to facilitate efficiency and basic safety in scientific practice.… Continue reading After approval of warfarin in 1954, vitamin K antagonists (VKAs) continued