The immunosuppressive and antiinflammatory cytokine interleukin (IL) 10 selectively upregulates the expression of the CC chemokine receptors CCR5, 2, and 1 in human being monocytes by prolonging their mRNA half-life. chemokine production both in vitro and in vivo (1C3). Contrary to this, molecules with immunosuppressive and antiinflammatory activity, such as IL-10 and glucocorticoid hormones, inhibit… Continue reading The immunosuppressive and antiinflammatory cytokine interleukin (IL) 10 selectively upregulates the