Background Statins are shown to have cholesterol-independent properties such as anti-inflammation and immunomodulation. could prevent the apoptosis induced by atorvastatin. By Western blot we could not detect any switch in the activation of c-jun N-terminal kinase (JNK). Conclusions Atorvastatin induces apoptosis in triggered HSCs acting through an ERK-dependent cleavage of Bid AT13387 manufacture and a… Continue reading Background Statins are shown to have cholesterol-independent properties such as anti-inflammation