Open in another window Some novel 3,5-diamino-1,2,4-triazole benzyl ureas was informed they have powerful anaplastic lymphoma kinase (ALK) inhibition exemplified by 15a, 20a, and 23a, which exhibited antiproliferative IC50 values of 70, 40, and 20 nM in Tel-ALK transformed Ba/F3 cells, respectively. in addition has been found that germline mutations in ALK will be the… Continue reading Open in another window Some novel 3,5-diamino-1,2,4-triazole benzyl ureas was informed