Background: Loss of development inhibitory response to transforming growth factor-(TGF-resistance. in expression. Notably, FOXG1 was able to inhibit the promoter activity in a p53-impartial manner by transient reporter assays. Conclusion Our results suggest that FOXG1 acts as an oncoprotein inhibiting TGF-transcription. (TGF-receptors and Smad transducer proteins (Hu in buy TTP-22 mediating these cellular activities depends… Continue reading Background: Loss of development inhibitory response to transforming growth factor-(TGF-resistance. in