Background Acquired resistance to standard chemotherapy causes treatment failure in individuals with metastatic bladder malignancy. lines 5637 and RT4 were founded for the investigation of acquired resistance mechanisms. Cell lines transporting a stable lentiviral knockdown of the core autophagy regulator ATG5 were created from chemosensitive 5637 and chemoresistant 5637rGEMCI20 and 5637rCDDP1000 cell lines. Cell death… Continue reading Background Acquired resistance to standard chemotherapy causes treatment failure in individuals