Cytotoxic necrotizing factors from (CNF1, CNF2) and (CNFy) share toxin (PMT). and 0.0051 for CNFy-CNF2 in (a) and 0.000001 for CNF2-CNF1, 0.0000001 for CNFy-CNF1 and 0.00019 for CNFy-CNF2 in (b). Comparable dose-dependent improvement of CNF1-mediated SRE-luciferase activity was noticed for additional endosomal acidification inhibitors, such as for example monensin and nigericin (Physique 2a,b, respectively). Monensin… Continue reading Cytotoxic necrotizing factors from (CNF1, CNF2) and (CNFy) share toxin (PMT).