Tag: CCT129202

Ghrelin, an endogenous ligand from the growth hormone secretagogue receptor (GHS-R),

Ghrelin, an endogenous ligand from the growth hormone secretagogue receptor (GHS-R), is the only circulating agent to powerfully promote a positive energy balance. of 50 and 500 nmolkg?1day?1 using implanted subcutaneous minipumps in rats. High-dose treatment with single agonists or ghrelin increased body weight gain by promoting fat mass, whereas BIM-28131 was the only one… Continue reading Ghrelin, an endogenous ligand from the growth hormone secretagogue receptor (GHS-R),

The radiotracer 3-[18F]fluoro-5-(2-pyridinylethynyl)benzonitrile or [18F]FPEB is really a promising PET imaging

The radiotracer 3-[18F]fluoro-5-(2-pyridinylethynyl)benzonitrile or [18F]FPEB is really a promising PET imaging agent for the metabotropic glutamate subtype 5 receptor (mGluR5). 250.0611; discovered: 250.0608. 2.2 One-pot synthesis of 3-fluoro-5-[(pyridine-2-yl)ethynyl]benzonitrile CCT129202 (7 FPEB) Substance 7 was ready being a yellowish great in 72% produce (478.2 mg 2.15 mmol) in an operation much like that for substance 5… Continue reading The radiotracer 3-[18F]fluoro-5-(2-pyridinylethynyl)benzonitrile or [18F]FPEB is really a promising PET imaging