Supplementary MaterialsSupplementary Data. This involves a novel mechanism of translational silencing mediated by binding of a cytosolic protein complex to specific elements within the 3 UTRs of target mRNAs. We first identified this mechanism in a model of IFN- induced synthesis of ceruloplasmin (Cp) Cd151 in human monocytes (6C8). These studies showed that IFN- treatment… Continue reading Supplementary MaterialsSupplementary Data. This involves a novel mechanism of translational silencing