We present herein that the ability of 5 different monomeric IgEs (mIgEs) to enhance murine bone marrow-derived mast cell (BMMC) survival correlates with their ability to stimulate extracellular calcium (Ca++) entry. (MKP) rather than MEK. IgE-induced ROS generation, unlike that induced by IgE+Ag, is not mediated CREB3L3 by 5-lipoxygenase (5-LO). Moreover, ROS inhibitors, which block… Continue reading We present herein that the ability of 5 different monomeric IgEs