Intestinal microbiota metabolism of choline/phosphatidylcholine produces trimethylamine (TMA) which is usually further metabolized to a proatherogenic species trimethylamine-N-oxide (TMAO). adverse cardiac events (MI stroke or death) but only among subjects with concurrently high TMAO levels. Chronic dietary L-carnitine supplementation in mice significantly altered cecal microbial composition markedly enhanced synthesis of TMA/TMAO and increased atherosclerosis but… Continue reading Intestinal microbiota metabolism of choline/phosphatidylcholine produces trimethylamine (TMA) which is usually