Alloimmune platelet refractoriness (alloPR) among actively bleeding surgical patients with thrombocytopenia represents a life-threatening problem. Introduction Alloimmunization to human leukocyte antigens (HLA) remains a major hurdle in achieving successful transplantation and is the primary cause of alloimmune platelet refractoriness (alloPR) [1-3]. Platelet transfusion support of HLA allosensitized patients presents distinct problems for the blood transfusion… Continue reading Alloimmune platelet refractoriness (alloPR) among actively bleeding surgical patients with thrombocytopenia