The onset and regulation of mitosis is dependent on phosphorylation of a wide array of proteins. acid a phosphomimetic or to alanine an unmodifiable residue result in an increase in cells in prophase and an increase in anaphase/telophase bridges respectively. SILAC-coupled mass spectrometry shows that phosphorylated H3T80 (H3T80ph) preferentially interacts with histones H2A and H4… Continue reading The onset and regulation of mitosis is dependent on phosphorylation of