Both insulin resistance (type II diabetes) and β-amyloid (Aβ) oligomers are implicated in Alzheimer’s disease (AD). and tau (Ser422) in cultured hippocampal neurons whereas JNK inhibition clogged these reactions. The omega-3 fatty acid docosahexaenoic acid (DHA) similarly inhibited JNK and the phosphorylation of IRS-1 and tau in cultured hippocampal neurons. Feeding 3xTg-AD transgenic mice a… Continue reading Both insulin resistance (type II diabetes) and β-amyloid (Aβ) oligomers are