Background Premature neonates frequently require oxygen supplementation like a therapeutic treatment that, while necessary, also exposes the lung to significant oxidant stress. paracellular leak was associated with modified claudin expression, where claudin-3 and claudin-18 were downregulated at both the mRNA and protein level. Claudin-4 and claudin-5 mRNA were also decreased, although protein manifestation of these… Continue reading Background Premature neonates frequently require oxygen supplementation like a therapeutic treatment