The p53 tumor suppressor proteins plays a critical role in cellular stress and cancer prevention. the cellular performance of p53 with the microRNA feedback pathways we developed a mathematical model of the core p53-MDM2 module coupled with three microRNA-mediated positive feedback loops involving miR-192 miR-34a and miR-29a. Simulations and bifurcation analysis in relationship to extrinsic… Continue reading The p53 tumor suppressor proteins plays a critical role in cellular
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(gene encoding β-catenin in allele dramatically inhibited mutation-induced colon polyposis and
(gene encoding β-catenin in allele dramatically inhibited mutation-induced colon polyposis and greatly extended hemizygous dosage markedly inhibited boosts in β-catenin amounts in the cytoplasm and nucleus following Metformin HCl inactivation in digestive tract epithelium with attenuated appearance of essential β-catenin/TCF-regulated focus on genes Metformin HCl including those encoding the EphB2/B3 receptors the stem cell marker… Continue reading (gene encoding β-catenin in allele dramatically inhibited mutation-induced colon polyposis and