Variations of post-translational modifications are important for stability and behavior of therapeutic antibodies. benzoylecgonine and cocaethylene by fluorescence quenching of intrinsic antibody tyrosine and tryptophan fluorescence resulting from binding of these drugs. Binding constants obtained from fluorescence quenching measurements are in agreement with recently published radioligand and ELISA binding assays. The dissociation constants determined for… Continue reading Variations of post-translational modifications are important for stability and behavior of