A host of diabetes-related insults to the central nervous PLA2G4F/Z system (CNS) have been clearly documented in type-1 and -2 diabetic patients as well as experimental animal models. CNS disorders. Changes in plasma glucose levels (hyper- or hypoglycemia) have been associated with altered BBB transport functions (e.g. glucose insulin choline amino acids etc.) integrity (tight… Continue reading A host of diabetes-related insults to the central nervous PLA2G4F/Z
Tag: PLA2G4F/Z
CrkRS (Cdc2-related kinase Arg/Ser) or cyclin-dependent kinase 12 (CKD12) Ibutamoren (MK-677)
CrkRS (Cdc2-related kinase Arg/Ser) or cyclin-dependent kinase 12 (CKD12) Ibutamoren (MK-677) is a serine/threonine kinase thought to coordinate transcription and RNA splicing. CDK12/CrkRS but usually do not contain CDK9 a presumed partner of cyclin K. Evaluation of comprehensive RNA-Seq data implies that the 65-kDa cyclin K1 isoform may be the mostly expressed type across numerous… Continue reading CrkRS (Cdc2-related kinase Arg/Ser) or cyclin-dependent kinase 12 (CKD12) Ibutamoren (MK-677)