Ceramidases cleave the N-acyl linkages of ceramide to create sphingosine and

Ceramidases cleave the N-acyl linkages of ceramide to create sphingosine and its own subsequent item sphingosine-1-phosphate (S1P). and Cu2+, while Ca2+ stimulates the experience. Phosphatidic acid, phosphatidylserine and phosphatidylcholine inhibited enzyme activity in low concentrations completely. Thiol-containing substances inhibited the CBCDase activity. Among the nucleotides, ADP, UMP, and TMP inhibited the enzyme activity at low… Continue reading Ceramidases cleave the N-acyl linkages of ceramide to create sphingosine and