Supplementary Materials1_si_001. substrate-promiscuous variant from the fatty acidity monooxygenase P450BM3 (settings towards the C9 carbon in 3. As opposed to FL#62, wild-type P450BM3 demonstrated minimal PTL-oxidation activity (30 TTN), making the epoxide 2 as the just product. Substances 1 and 2 match normally taking place derivatives of parthenolide, 51, 52 whereas compound 4 has been… Continue reading Supplementary Materials1_si_001. substrate-promiscuous variant from the fatty acidity monooxygenase P450BM3 (settings