Supplementary MaterialsFigure S1: Controls. site. Primers b-3 confirm integration of the Neor cassette and exons 3-5. Digestion of this product with gene deletion in mice and TRIM3 overexpression in cultured neurons both suggested that the E3-ligase function of TRIM3 is not involved in KIF21B degradation, however TRIM3 depletion reduces the motility of the motor. Together,… Continue reading Supplementary MaterialsFigure S1: Controls. site. Primers b-3 confirm integration of the