Although norepinephrine (NE) does not typically modulate cocaine self-administration under traditional schedules of reinforcement it is required for different inducers of the reinstatement of cocaine-seeking behavior via activation of multiple adrenergic receptor subtypes. saline. Yohimbine (2.5?mg/kg) was purchased from Sigma and dissolved in distilled water. Food Training All rats were trained to lever-press for food… Continue reading Although norepinephrine (NE) does not typically modulate cocaine self-administration under traditional