Background Modification or Recovery of CFTR function in local epithelia may be the best objective of CF therapeutics advancement. the F-CFTR mouse as well as the bitransgenic CFTR mouse corrected in the gut but null in the lung and airways. WT/F heterozygotes got an intermediate phenotype in regards to to CFTR agonist replies in in… Continue reading Background Modification or Recovery of CFTR function in local epithelia may