Eukaryotic RNAs with early termination codons (PTCs) are eliminated by nonsense-mediated decay (NMD). SMG6-catalyzed endocleavage may also take place during individual NMD (Huntzinger et al. 2008; Rabbit polyclonal to PNPLA2 Eberle et al. 2009). Nevertheless, the level to which this plays a part in the entire degradation of endogenous non-sense RNAs continues to be questioned… Continue reading Eukaryotic RNAs with early termination codons (PTCs) are eliminated by nonsense-mediated