Fibroblast growth factors (FGFs) negatively regulate long bone development by inhibiting the proliferation of chondrocytes that accumulate in the G1 phase of the cycle following FGF treatment. likely caused by increased activity and expression of the Myt1 kinase. FGF1 also caused dephosphorylation of the CDC25C phosphatase. That however appears due the inactivation of cyclin B1/CDK1… Continue reading Fibroblast growth factors (FGFs) negatively regulate long bone development by inhibiting