Two major human diseases caused by filariid nematodes are onchocerciasis or river blindness and lymphatic filariasis which can lead to elephantiasis. worms and in inhibiting the molting of L3s of with IC50 values in the low micromolar to nanomolar range. Auranofin experienced an approximately 43-fold higher IC50 against the microfilariae of compared with the IC50… Continue reading Two major human diseases caused by filariid nematodes are onchocerciasis or