The G1 kinase CDK4 is amplified or overexpressed in a few individual tumors and promotes tumorigenesis by inhibiting known tumor suppressors. individual non-Hodgkin B cell lymphoma. Collectively these results set up a context-specific tumor suppressor function for CDK4 that prevents genomic instability which plays a part in B cell lymphoma. Furthermore our data claim that… Continue reading The G1 kinase CDK4 is amplified or overexpressed in a few