To recognize and characterize anti-citrullinated glucose-6-phosphate isomerase (GPI) peptide antibodies in individuals with rheumatoid arthritis (RA). with disease activity [8]. Glucose-6-phosphate isomerase (GPI) a major glycolytic enzyme was first described as an arthritogenic target in the K/B×N T cell receptor transgenic mouse model and arthritis was sustained almost completely by autoantibodies to GPI [9 10… Continue reading To recognize and characterize anti-citrullinated glucose-6-phosphate isomerase (GPI) peptide antibodies in