Supplementary MaterialsTransparent reporting form. as a ratio of red to green fluorescence intensity. Compared to age-matched WT/Het siblings, mutants exhibited significantly lower JC-1 fluorescence ratios, indicating that the mitochondria are depolarized (Figure 2C) (WT/Het: 0.25??0.24 n?=?8 fish, Mutant: 0.05??0.07 n?=?8 fish, Mann-Whitney U test, p? ?0.01, mean ratio??SD). These results suggest that mitochondrial activity is… Continue reading Supplementary MaterialsTransparent reporting form. as a ratio of red to green