In mutants telomeric DNA is degraded and cell-cycle progression is inhibited. aspects of eukaryotic cell biology. LINEAR chromosomes are a feature of all eukaryotes. The single-celled model eukaryote cells can tolerate 32 or more chromosome ends throughout its cell cycle, a single double-stranded DNA break (DSB) elsewhere in the genome elicits a swift and exact… Continue reading In mutants telomeric DNA is degraded and cell-cycle progression is inhibited.